Deutsch
 
Hilfe Datenschutzhinweis Impressum
  DetailsucheBrowse

Datensatz

DATENSATZ AKTIONENEXPORT
  Simultaneous PET-MRI: a new approach for functional and morphological imaging

Judenhofer, M., Wehrl, H., Newport, D., Catana, C., Siegel, S., Becker, M., et al. (2008). Simultaneous PET-MRI: a new approach for functional and morphological imaging. Nature Medicine, 14(4), 459-465. doi:10.1038/nm1700.

Item is

Basisdaten

einblenden: ausblenden:
Genre: Zeitschriftenartikel

Externe Referenzen

einblenden:
ausblenden:
externe Referenz:
https://www.nature.com/articles/nm1700.pdf (Verlagsversion)
Beschreibung:
-
OA-Status:

Urheber

einblenden:
ausblenden:
 Urheber:
Judenhofer, MS, Autor
Wehrl, HF, Autor
Newport, DF, Autor
Catana, C, Autor
Siegel, SB, Autor
Becker, M, Autor
Thielscher, A1, 2, Autor           
Kneiling, M, Autor
Lichy, MP, Autor
Eichner, M, Autor
Klingel, K, Autor
Reischl, G, Autor
Widmaier, S, Autor
Röcken, M, Autor
Nutt, RE, Autor
Machulla, H-J, Autor
Uludag, K1, 2, Autor           
Cherry, SR, Autor
Claussen, CD, Autor
Pichler, BJ, Autor
Affiliations:
1Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_2528700              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

Inhalt

einblenden:
ausblenden:
Schlagwörter: -
 Zusammenfassung: Noninvasive imaging at the molecular level is an emerging field in biomedical research. This paper introduces a new technology synergizing two leading imaging methodologies: positron emission tomography (PET) and magnetic resonance imaging (MRI). Although the value of PET lies in its high-sensitivity tracking of biomarkers in vivo, it lacks resolving morphology. MRI has lower sensitivity, but produces high soft-tissue contrast and provides spectroscopic information and functional MRI (fMRI). We have developed a three-dimensional animal PET scanner that is built into a 7-T MRI. Our evaluations show that both modalities preserve their functionality, even when operated isochronously. With this combined imaging system, we simultaneously acquired functional and morphological PET-MRI data from living mice. PET-MRI provides a powerful tool for studying biology and pathology in preclinical research and has great potential for clinical applications. Combining fMRI and spectroscopy with PET paves the way for a new perspective in molecular imaging.

Details

einblenden:
ausblenden:
Sprache(n):
 Datum: 2008-04
 Publikationsstatus: Erschienen
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: -
 Identifikatoren: DOI: 10.1038/nm1700
BibTex Citekey: 5386
 Art des Abschluß: -

Veranstaltung

einblenden:

Entscheidung

einblenden:

Projektinformation

einblenden:

Quelle 1

einblenden:
ausblenden:
Titel: Nature Medicine
  Andere : Nat. Med.
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: New York, NY : Nature Pub. Co.
Seiten: - Band / Heft: 14 (4) Artikelnummer: - Start- / Endseite: 459 - 465 Identifikator: ISSN: 1078-8956
CoNE: https://pure.mpg.de/cone/journals/resource/954925606824