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  Imaging in vivo: watching the brain in action

Kerr, J., & Denk, W. (2008). Imaging in vivo: watching the brain in action. Nature Reviews Neuroscience, 9(3), 195-205. doi:10.1038/nrn2338.

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https://www.nature.com/articles/nrn2338.pdf (Publisher version)
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Kerr, JND1, 2, 3, Author           
Denk, W, Author
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1Former Research Group Network Imaging, Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_2528697              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              
3Research Group Neural Population Imaging, Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497807              

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 Abstract: The appeal of in vivo cellular imaging to any neuroscientist is not hard to understand: it is almost impossible to isolate individual neurons while keeping them and their complex interactions with surrounding tissue intact. These interactions lead to the complex network dynamics that underlie neural computation which, in turn, forms the basis of cognition, perception and consciousness. In vivo imaging allows the study of both form and function in reasonably intact preparations, often with subcellular spatial resolution, a time resolution of milliseconds and a purview of months. Recently, the limits of what can be achieved in vivo have been pushed into terrain that was previously only accessible in vitro, due to advances in both physical-imaging technology and the design of molecular contrast agents.

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 Dates: 2008-03
 Publication Status: Published in print
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 Identifiers: DOI: 10.1038/nrn2338
BibTex Citekey: 5388
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Title: Nature Reviews Neuroscience
Source Genre: Journal
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Publ. Info: England : Nature Pub. Group
Pages: - Volume / Issue: 9 (3) Sequence Number: - Start / End Page: 195 - 205 Identifier: ISSN: 1471-003X
CoNE: https://pure.mpg.de/cone/journals/resource/110985821000937