English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Crossmodal Propagation of Sensory-Evoked and Spontaneous Activity in the Rat Neocortex

Takagaki, K., Zhang, C., Wu, J., & Lippert, M. (2008). Crossmodal Propagation of Sensory-Evoked and Spontaneous Activity in the Rat Neocortex. Neuroscience Letters, 431(3), 191-196. doi:10.1016/j.neulet.2007.11.069.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-CA5B-9 Version Permalink: http://hdl.handle.net/21.11116/0000-0003-317A-D
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Takagaki, K, Author
Zhang , C, Author
Wu, JY, Author
Lippert, MT1, Author              
Affiliations:
1External Organizations, ou_persistent22              

Content

show
hide
Free keywords: -
 Abstract: In the cortex, neural responses to crossmodal stimulation are seen both in higher association areas and in primary sensory areas, and are thought to play a role in integration of crossmodal sensations. We used voltage-sensitive dye imaging (VSDI) to study the spatiotemporal characteristics of such crossmodal neural activity. We imaged three cortical regions in rat: primary visual cortex (V1), barrel field of primary somatosensory cortex (S1bf) and parietal association area (PA, flanked by V1 and S1bf). We find that sensory-evoked population activity can propagate in the form of a distinct propagating wave, robustly in either crossmodal direction. In single trials, the waveforms changed continuously during propagation, with dynamic variability from trial to trial, which we interpret as evidence for cortical involvement in the spreading process. To further characterize the functional anatomy of PA, we also studied the propagation of spontaneous sleep-like waves in this area. Using a novel flow-detection algorithm, we detected a propagation bias within PA of spontaneous waves—these tend to propagate parallel to the crossmodal axis, rather than orthogonal to it. Taken together, these findings demonstrate that intracortical networks show pre-attentive crossmodal propagation of activity, and suggest a potential mechanism for the establishment of crossmodal integration.

Details

show
hide
Language(s):
 Dates: 2008-02
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1016/j.neulet.2007.11.069
BibTex Citekey: 5201
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Neuroscience Letters
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Amsterdam : Elsevier
Pages: - Volume / Issue: 431 (3) Sequence Number: - Start / End Page: 191 - 196 Identifier: ISSN: 0304-3940
CoNE: https://pure.mpg.de/cone/journals/resource/954925512448