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  BOLD sensitivity to cortical activation induced by microstimulation: comparison to visual stimulation

Sultan, F., Augath, M., & Logothetis, N. (2007). BOLD sensitivity to cortical activation induced by microstimulation: comparison to visual stimulation. Magnetic Resonance Imaging, 25(6), 754-759. doi:10.1016/j.mri.2007.03.014.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-CC93-8 Version Permalink: http://hdl.handle.net/21.11116/0000-0003-BC80-8
Genre: Journal Article

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 Creators:
Sultan, F, Author
Augath, M1, 2, Author              
Logothetis, NK1, 2, Author              
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: Electrical microstimulation via intracortical electrodes is a widely used method for deducing functions of the brain. In this study, we compared the spatial extent and amplitude of BOLD responses evoked by intracortical electrical stimulation in primary visual cortex with BOLD activations evoked by visual stimulation. The experiments were performed in anesthetized rhesus monkeys. Visual stimulation yielded activities larger than predicted from the well-established visual magnification factor. However, electrical microstimulation yielded an even greater spread of the BOLD response. Our results confirm that the effects of electrical microstimulation extend beyond the brain region expected to be excited by direct current spread.

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 Dates: 2007-07
 Publication Status: Published in print
 Pages: -
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 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1016/j.mri.2007.03.014
BibTex Citekey: 5723
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Title: Magnetic Resonance Imaging
Source Genre: Journal
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Publ. Info: New York : Elsevier
Pages: - Volume / Issue: 25 (6) Sequence Number: - Start / End Page: 754 - 759 Identifier: ISSN: 0730-725X
CoNE: https://pure.mpg.de/cone/journals/resource/954925533026