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  Dynamics of Lactate Concentration and BOLD Effect Upon Repeated Identical Visual Stimuli

Mangia, S., Tkac, I., Logothetis, N., Van de Moortele, P.-F., Gruetter, R., & Ugurbil, K. (2007). Dynamics of Lactate Concentration and BOLD Effect Upon Repeated Identical Visual Stimuli. Poster presented at 2007 Joint Annual Meeting ISMRM-ESMRMB, Berlin, Germany.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0013-CDD5-E Version Permalink: https://hdl.handle.net/21.11116/0000-0004-052A-8
Genre: Poster

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https://cds.ismrm.org/ismrm-2007/files/1_program.pdf (Abstract)
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 Creators:
Mangia, S, Author
Tkac, I, Author
Logothetis, NK1, 2, Author           
Van de Moortele , P-F, Author
Gruetter, R, Author
Ugurbil, K, Author
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: In vivo 1H NM spectroscopy at 7 T was utilized to measure the changes of lactate concentration upon repeated identical visual stimuli, each lasting 2 min. The amplitude of these changes was attenuated from the initial value of 0.2 μmol/g and gradually disappeared in the noise. In sharp contrast, the Blood Oxygen Level Dependent (BOLD) effect was persistent during the whole paradigm. This finding may suggest a differential adaptation of cortical output that
is not reflected at the level of the global excitation-inhibition activity of the cortical canonical circuits.

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 Dates: 2007-05
 Publication Status: Issued
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 Rev. Type: -
 Identifiers: BibTex Citekey: MangiaTLVGU2077
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Title: 2007 Joint Annual Meeting ISMRM-ESMRMB
Place of Event: Berlin, Germany
Start-/End Date: 2007-05-19 - 2007-05-25

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Title: 2007 Joint Annual Meeting ISMRM-ESMRMB
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 1375 Start / End Page: 289 Identifier: -