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  Extravascular BOLD Effect for Different Size Blood Vessels Over a Large Range of Magnetic Fields

Uludag, K., Müller-Bierl, B., & Ugurbil, K. (2007). Extravascular BOLD Effect for Different Size Blood Vessels Over a Large Range of Magnetic Fields. In 2007 Joint Annual Meeting ISMRM-ESMRMB (pp. 60).

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-CDD7-A Version Permalink: http://hdl.handle.net/21.11116/0000-0004-054F-F
Genre: Meeting Abstract

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 Creators:
Uludag, K1, 2, Author              
Müller-Bierl, BM, Author              
Ugurbil, K, Author
Affiliations:
1Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_2528700              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: The blood oxygenation level dependent (BOLD) signal depends on physiological changes which affect the signal behavior of protons both in the intra- and extravascular tissue space. The functional dependency of the extravascular signal on the oxygenation fraction Y and on cerebral blood volume (CBV) can currently only be evaluated by numerical simulations. We provide analytical expressions for relaxation rates R2* and R2 depending on Y, B0 up to 9.4 T, and CBV for different size cylinders (approx. 3, 6, 20 μm). These results allow to model stimulus evoked BOLD signal changes for GRE and SE at different field strengths.

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 Dates: 2007-05
 Publication Status: Published in print
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 Identifiers: BibTex Citekey: 4474
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Title: 2007 Joint Annual Meeting ISMRM-ESMRMB
Place of Event: Berlin, Germany
Start-/End Date: 2007-05-19 - 2007-05-25

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Title: 2007 Joint Annual Meeting ISMRM-ESMRMB
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 258 Start / End Page: 60 Identifier: -