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  Spatial specificity of CBV and BOLD fMRI in monkey striate cortex at 4.7T and 7T

Zappe, A.-C., Logothetis, N., & Goense, J. (2007). Spatial specificity of CBV and BOLD fMRI in monkey striate cortex at 4.7T and 7T. In 2007 Joint Annual Meeting ISMRM-ESMRMB (pp. 136).

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 Creators:
Zappe, A-C1, 2, Author           
Logothetis, NK1, 2, Author           
Goense, JBM1, 2, Author           
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: High resolution fMRI allows us to determine more accurately the origins of the fMRI signal. This has shown that even at
high field, the GE-BOLD signal has still a large vascular contribution [1]. Alternative methods like SE- and monocrystalline iron oxide nanocolloid (MION)-based methods have been shown to be spatially more specific than conventional BOLD, and are able to reveal functional subunits in the cortex [2-6]. Here we compare the specificity of BOLD and CBV fMRI methods in the macaque; its striate cortex shows very obvious laminar structure in anatomical images, allowing accurate determination of the precise location of the fMRI activation.

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 Dates: 2007-05
 Publication Status: Issued
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 Identifiers: BibTex Citekey: 4428
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Title: 2007 Joint Annual Meeting ISMRM-ESMRMB
Place of Event: Berlin, Germany
Start-/End Date: 2007-05-19 - 2007-05-25

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Title: 2007 Joint Annual Meeting ISMRM-ESMRMB
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 616 Start / End Page: 136 Identifier: -