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  Insights into the dynamics of hemodynamic response to millisecond stimulus duration: A fMRI and VEP study

Yesilyurt, B., Whittingstall, K., Ugurbil, K., & Uludag, K. (2007). Insights into the dynamics of hemodynamic response to millisecond stimulus duration: A fMRI and VEP study. In 2007 Joint Annual Meeting ISMRM-ESMRMB (pp. 39).

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-CDED-9 Version Permalink: http://hdl.handle.net/21.11116/0000-0004-0549-5
Genre: Meeting Abstract

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Yesilyurt, B1, 2, Author              
Whittingstall, K2, 3, Author              
Ugurbil, K, Author
Uludag, K1, 2, Author              
Affiliations:
1Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_2528700              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              
3Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              

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 Abstract: In a previous study, we have shown that in human subjects it is possible to detect blood oxygenation level dependent (BOLD) signal changes evoked by a visual stimulus presented only for 5 ms. Moreover, we observed that at this ultrashort stimulus duration a) the response is highly non-linear compared to 50ms, 250ms and 1s stimulus b) the extrapolated intercept at 0ms stimulus duration was not zero. That is, below specific stimulus duration the hemodynamic response remains constant. In this study, we have expanded our previous investigation on the temporal behaviour of the BOLD response by zooming into the time scale of stimulus durations as short as 0.1 to 5ms, in order to evaluate if there is indeed a minimum hemodynamic response. Moreover, in order to gain insights about the dynamics of neural response at ultrashort stimulus durations, we also performed VEP recordings to complement the fMRI data.

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 Dates: 2007-05
 Publication Status: Published in print
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 Identifiers: BibTex Citekey: 5938
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Title: 2007 Joint Annual Meeting ISMRM-ESMRMB
Place of Event: Berlin, Germany
Start-/End Date: 2007-05-19 - 2007-05-25

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Title: 2007 Joint Annual Meeting ISMRM-ESMRMB
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 191 Start / End Page: 39 Identifier: -