English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Neural Correlates of Perceptual Choice and Decision Making during Fear–Disgust Discrimination

Thielscher, A., & Pessoa, L. (2007). Neural Correlates of Perceptual Choice and Decision Making during Fear–Disgust Discrimination. The Journal of Neuroscience, 27(11), 2908-2917. doi:10.1523/JNEUROSCI.3024-06.2007.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-CE6B-3 Version Permalink: http://hdl.handle.net/21.11116/0000-0003-CC40-F
Genre: Journal Article

Files

show Files

Locators

show
hide
Description:
-

Creators

show
hide
 Creators:
Thielscher, A1, 2, Author              
Pessoa, L, Author
Affiliations:
1Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_2528700              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

Content

show
hide
Free keywords: -
 Abstract: In the present study, we tested the hypothesis that brain activation would reflect perceptual choices. To probe this question, we used functional magnetic resonance imaging (fMRI) during a challenging fear–disgust, two-choice discrimination task. We investigated how moment-to-moment fluctuations in fMRI signals were correlated with perceptual choice by computing a choice probability index that quantified how well behavioral choice could be predicted by single-trial fMRI amplitude. Our analyses revealed that reporting a neutral face as "fearful" was associated with activation in a broad network of brain regions that process emotionally arousing stimuli, whereas reporting a neutral face as "disgusted" was associated with activation in a focused set of sites that included the putamen and anterior insula. Responses predictive of perceptual reports were not only observed at the group level but also at the single-subject level. Thus, voxel-by-voxel fluctuations in fMRI amplitude for an individual participant could be used to reliably predict the perceptual choice of individual trials for that subject. In addition to the investigation of choice, we also isolated the neural correlates of decision making per se by using reaction time as an index of decision processes. Overall, our findings revealed that brain responses dynamically shifted according to perceptual choices. In addition, the neural correlates of decision making involved at least the anterior cingulate cortex, middle frontal gyrus, and inferior frontal gyrus/insula, consistent with recent proposals that decisions may emerge from distributed processes.

Details

show
hide
Language(s):
 Dates: 2007-03
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1523/JNEUROSCI.3024-06.2007
BibTex Citekey: 4420
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: The Journal of Neuroscience
  Other : J. Neurosci.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Baltimore, MD : The Society
Pages: - Volume / Issue: 27 (11) Sequence Number: - Start / End Page: 2908 - 2917 Identifier: ISSN: 0270-6474
CoNE: https://pure.mpg.de/cone/journals/resource/954925502187