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  Reduced field-of-view MRI using outer volume suppression for spinal cord diffusion imaging

Wilm, B., Svensson, J., Henning, A., Pruessmann, K., Boesiger, P., & Kollias, S. (2007). Reduced field-of-view MRI using outer volume suppression for spinal cord diffusion imaging. Magnetic Resonance in Medicine, 57(3), 625-630. doi:10.1002/mrm.21167.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-CE6F-C Version Permalink: http://hdl.handle.net/21.11116/0000-0003-CC70-9
Genre: Journal Article

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Wilm, BJ, Author
Svensson, J, Author
Henning, Anke1, Author              
Pruessmann, KP, Author
Boesiger, P, Author
Kollias, SS, Author
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1Institute of Biomedical Engineering, University and ETH Zurich, ou_persistent22              

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 Abstract: A spin-echo single-shot echo-planar imaging (SS-EPI) technique with a reduced field of view (FOV) in the phase-encoding direction is presented that simultaneously reduces susceptibility effects and motion artifacts in diffusion-weighted (DW) imaging (DWI) of the spinal cord at a high field strength (3T). To minimize aliasing, an outer volume suppression (OVS) sequence was implemented. Effective fat suppression was achieved with the use of a slice-selection gradient-reversal technique. The OVS was optimized by numerical simulations with respect to T1 relaxation times and B1 variations. The optimized sequence was evaluated in vitro and in vivo. In simulations the optimized OVS showed suppression to <0.25 and ∼3 in an optimal and worst-case scenario, respectively. In vitro measurements showed a mean residual signal of <0.95 ± 0.42 for all suppressed areas. In vivo acquisition with 0.9 × 1.05 mm2 in-plane resolution resulted in artifact-free images. The short imaging time of this technique makes it promising for clinical studies.

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 Dates: 2007-03
 Publication Status: Published in print
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 Rev. Type: -
 Identifiers: DOI: 10.1002/mrm.21167
BibTex Citekey: WilmSHPBK2007
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Title: Magnetic Resonance in Medicine
Source Genre: Journal
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Publ. Info: New York : Wiley-Liss
Pages: - Volume / Issue: 57 (3) Sequence Number: - Start / End Page: 625 - 630 Identifier: ISSN: 0740-3194
CoNE: https://pure.mpg.de/cone/journals/resource/954925538149