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  Time-resolved 3D contrast-enhanced MRA with GRAPPA on a 1.5-T system for imaging of craniocervical vascular disease: initial experience

Meckel, S., Mekle, R., Taschner, C., Haller, S., Scheffler, K., Radü, E.-W., et al. (2006). Time-resolved 3D contrast-enhanced MRA with GRAPPA on a 1.5-T system for imaging of craniocervical vascular disease: initial experience. Neuroradiology, 48(5), 291-299. doi:10.1007/s00234-006-0052-9.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-D1DD-0 Version Permalink: http://hdl.handle.net/21.11116/0000-0004-8678-E
Genre: Journal Article

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Meckel, S, Author
Mekle, R, Author
Taschner, C, Author
Haller, S, Author
Scheffler, K1, Author              
Radü, E-W, Author
Wetzel, SG, Author
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1External Organizations, ou_persistent22              

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 Abstract: Introduction: For three-dimensional (3D) imaging with magnetic resonance angiography (MRA) of the cerebral and cervical circulation, both a high temporal and a high spatial resolution with isovolumetric datasets are of interest. In an initial evaluation, we analyzed the potential of contrast-enhanced (CE) time-resolved 3D-MRA as an adjunct for neurovascular MR imaging. Methods: In ten patients with various cerebrovascular disorders and vascularized tumors in the cervical circulation, high-speed MR acquisition using parallel imaging with the GeneRalized Autocalibrating Partially Parallel Acquisitions (GRAPPA) algorithm on a 1.5-T system with a temporal resolution of 1.5 s per dataset and a nearly isovolumetric spatial resolution was applied. The results were assessed and compared with those from conventional MRA and digital subtraction angiography (DSA). Results: CE time-resolved 3D-MRA enabled the visualization and characterization of high-flow arteriovenous shunts in cases of vascular malformations or hypervascularized tumors. In steno-occlusive disease, the method provided valuable additional information about altered vessel perfusion compared to standard MRA techniques such as time-of-flight (TOF) MRA. The use of a nearly isovolumetric voxel size allowed a free-form interrogation of 3D datasets. Its comparatively low spatial resolution was found to be the major limitation. Conclusion: In this preliminary analysis, CE time-resolved 3D-MRA was revealed to be a promising complementary MRA sequence that enabled the visualization of contrast flow dynamics in various types of neurovascular disorders and vascularized cervical tumors.

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 Dates: 2006-05
 Publication Status: Published in print
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 Rev. Method: -
 Identifiers: DOI: 10.1007/s00234-006-0052-9
BibTex Citekey: MeckelMTHSRW2006
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Title: Neuroradiology
Source Genre: Journal
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Publ. Info: Berlin : Springer-Verlag.
Pages: - Volume / Issue: 48 (5) Sequence Number: - Start / End Page: 291 - 299 Identifier: ISSN: 0028-3940
CoNE: https://pure.mpg.de/cone/journals/resource/954925428259