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  Laminar specificity of the SE-fMRI signal in monkey striate visual cortex

Goense, J., & Logothetis, N. (2006). Laminar specificity of the SE-fMRI signal in monkey striate visual cortex. Poster presented at 14th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2006), Seattle, WA, USA.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-D203-1 Version Permalink: http://hdl.handle.net/21.11116/0000-0004-C710-9
Genre: Poster

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 Creators:
Goense, JBM1, 2, Author              
Logothetis, NK1, 2, Author              
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: To relate fMRI signals to the underlying neural events, it is necessary to achieve a spatial resolution and specificity that permits visualization of the cortical functional units, e.g. cortical columns or laminae. Because the resolution of GE-fMRI is determined by intracortical veins and therefore limited, we used SEfMRI, which is weighted towards capillaries, to obtain specific BOLD responses. SE-EPI however is also sensitive to the venous fraction, potentially limiting spatial resolution. By decreasing the EPI acquisition window, we obtained highly specific functional activation. Activation was predominantly located in layer IV, while activation around surface vessels varied with acquisition window length.

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 Dates: 2006-05
 Publication Status: Published in print
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 Identifiers: BibTex Citekey: 4286
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Title: 14th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2006)
Place of Event: Seattle, WA, USA
Start-/End Date: 2006-05-06 - 2006-05-12

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Title: 14th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2006)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 3258 Start / End Page: 618 Identifier: -