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  Perfusion-based functional imaging in the monkey brain at 7T: investigations of CASL parameters

Zappe, A., Merkle, H., Pfeuffer, J., & Logothetis, N. (2006). Perfusion-based functional imaging in the monkey brain at 7T: investigations of CASL parameters. Poster presented at 14th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2006), Seattle, WA, USA.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-D207-A Version Permalink: http://hdl.handle.net/21.11116/0000-0004-C70E-D
Genre: Poster

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ISMRM-2006-Zappe.pdf (Any fulltext), 145KB
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ISMRM-2006-Zappe.pdf
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 Creators:
Zappe, A1, 2, Author              
Merkle, H, Author              
Pfeuffer, J1, 2, Author              
Logothetis, NK1, 2, Author              
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: Perfusion-based imaging in the monkey primary visual cortex was performed at 7 T applying continuous arterial spin labeling (CASL). Increased perfusion sensitivity and SNR at high magnetic field (due to larger T1) was further optimized using a custom-made three-coil setup with a separate neck labeling coil. We investigated the labeling parameters to obtain relative fCBF changes in the anaesthetized monkey. We report excellent functional activation of striate cortex at high resolution of 0.75x0.9mm2 in-plane. Interestingly, the optimal parameter set for obtaining highest signal changes of rCBF are different from the reported values for imaging gray matter CBF.

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 Dates: 2006-05
 Publication Status: Published in print
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 Identifiers: BibTex Citekey: 3970
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Title: 14th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2006)
Place of Event: Seattle, WA, USA
Start-/End Date: 2006-05-06 - 2006-05-12

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Title: 14th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2006)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 2135 Start / End Page: 419 Identifier: -