English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Identification of degenerate neuronal systems based on intersubject variability

Noppeney, U., Penny, W., Price, C., Flandin, G., & Friston, K. (2006). Identification of degenerate neuronal systems based on intersubject variability. NeuroImage, 30(3), 885-890. doi:10.1016/j.neuroimage.2005.10.010.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-D225-6 Version Permalink: http://hdl.handle.net/21.11116/0000-0004-8682-1
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Noppeney, U1, 2, Author              
Penny , WD, Author
Price, CJ, Author
Flandin, G, Author
Friston, KJ, Author
Affiliations:
1Research Group Cognitive Neuroimaging, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497804              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

Content

show
hide
Free keywords: -
 Abstract: Group studies implicitly assume that all subjects activate one common system to sustain a particular cognitive task. Intersubject variability is generally treated as well-behaved and uninteresting noise. However, intersubject variability might result from subjects engaging different degenerate neuronal systems that are each sufficient for task performance. This would produce a multimodal distribution of intersubject variability. We have explored this idea with the help of Gaussian Mixture Modeling and Bayesian model comparison procedures. We illustrate our approach using a crossmodal priming paradigm, in which subjects perform a semantic decision on environmental sounds or their spoken names that were preceded by a semantically congruent or incongruent picture or written name. All subjects consistently activated the superior temporal gyri bilaterally, the left fusiform gyrus and the inferior frontal sulcus. Comparing a One and Two Gaussian Mixture Model of the unexplained residuals provided very strong eviden ce for two groups with distinct activation patterns: 6 subjects exhibited additional activations in the superior temporal sulci bilaterally, the right superior frontal and central sulcus. 11 subjects showed increased activation in the striate and the right inferior parietal cortex. These results suggest that semantic decisions on auditory–visual compound stimuli might be accomplished by two overlapping degenerate neuronal systems.

Details

show
hide
Language(s):
 Dates: 2006-04
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1016/j.neuroimage.2005.10.010
BibTex Citekey: 3689
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: NeuroImage
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Orlando, FL : Academic Press
Pages: - Volume / Issue: 30 (3) Sequence Number: - Start / End Page: 885 - 890 Identifier: ISSN: 1053-8119
CoNE: https://pure.mpg.de/cone/journals/resource/954922650166