English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  A multivariate approach for processing magnetization effects in triggered event-related functional magnetic resonance imaging time series

Esposito, F., di Salle, F., Hennel, F., Santopaolo, O., Herdener, M., Scheffler, K., et al. (2006). A multivariate approach for processing magnetization effects in triggered event-related functional magnetic resonance imaging time series. NeuroImage, 30(1), 136-143. doi:10.1016/j.neuroimage.2005.09.012.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-D257-5 Version Permalink: http://hdl.handle.net/21.11116/0000-0004-868B-8
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Esposito, F, Author
di Salle, F, Author
Hennel, F, Author
Santopaolo, O, Author
Herdener, M1, Author              
Scheffler, K1, Author              
Goebel, R, Author
Seifritz, E, Author
Affiliations:
1External Organizations, ou_persistent22              

Content

show
hide
Free keywords: -
 Abstract: Triggered event-related functional magnetic resonance imaging requires sparse intervals of temporally resolved functional data acquisitions, whose initiation corresponds to the occurrence of an event, typically an epileptic spike in the electroencephalographic trace. However, conventional fMRI time series are greatly affected by non-steady-state magnetization effects, which obscure initial blood oxygen level-dependent (BOLD) signals. Here, conventional echo-planar imaging and a post-processing solution based on principal component analysis were employed to remove the dominant eigenimages of the time series, to filter out the global signal changes induced by magnetization decay and to recover BOLD signals starting with the first functional volume. This approach was compared with a physical solution using radiofrequency preparation, which nullifies magnetization effects. As an application of the method, the detectability of the initial transient BOLD response in the auditory cortex, which is elicited by the onset of acoustic scanner noise, was used to demonstrate that post-processing-based removal of magnetization effects allows to detect brain activity patterns identical with those obtained using the radiofrequency preparation. Using the auditory responses as an ideal experimental model of triggered brain activity, our results suggest that reducing the initial magnetization effects by removing a few principal components from fMRI data may be potentially useful in the analysis of triggered event-related echo-planar time series. The implications of this study are discussed with special caution to remaining technical limitations and the additional neurophysiological issues of the triggered acquisition.

Details

show
hide
Language(s):
 Dates: 2006-03
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1016/j.neuroimage.2005.09.012
BibTex Citekey: EspositoDHSHSGS2006
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: NeuroImage
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Orlando, FL : Academic Press
Pages: - Volume / Issue: 30 (1) Sequence Number: - Start / End Page: 136 - 143 Identifier: ISSN: 1053-8119
CoNE: https://pure.mpg.de/cone/journals/resource/954922650166