English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
 
 
DownloadE-Mail
  Development of visually evoked cortical activity in infant macaque monkeys studied longitudinally with fMRI

Kourtzi, Z., Augath, M., Logothetis, N., Movshon, A., & Kiorpes, L. (2006). Development of visually evoked cortical activity in infant macaque monkeys studied longitudinally with fMRI. Magnetic Resonance Imaging, 24(4), 359-366. doi:10.1016/j.mri.2005.12.025.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-D25F-6 Version Permalink: http://hdl.handle.net/21.11116/0000-0004-8690-1
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Kourtzi, Z1, 2, Author              
Augath, M1, 2, Author              
Logothetis, NK1, 2, Author              
Movshon, A, Author
Kiorpes, L, Author
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

Content

show
hide
Free keywords: -
 Abstract: We studied the development of visual activation longitudinally in two infant monkeys aged 103–561 days using the BOLD fMRI technique under opiate anesthesia and compared the results with those obtained in three adult animals studied under identical conditions. Visual activation in primary visual cortex, V1, was strong and reliable in monkeys of the youngest and oldest ages, showing that functional imaging techniques give qualitatively similar results in infants and adults. Visual activation in extrastriate areas involved in processing motion (MT/V5) and form (V4) was not evident in the younger animals, but became more adult-like in the older animals. This delayed onset of measurable BOLD responses in extrastriate visual cortex may reflect delayed development of visual responses in these areas, although at this stage it is not possible to rule out either effects of anesthesia or of changes in cerebral vascular response mechanisms as the cause. The demonstration of visually evoked BOLD responses in young monkeys shows that the BOLD fMRI technique can usefully be employed to address functional questions of brain development.

Details

show
hide
Language(s):
 Dates: 2006-03
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1016/j.mri.2005.12.025
BibTex Citekey: 3987
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Magnetic Resonance Imaging
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: New York : Elsevier
Pages: - Volume / Issue: 24 (4) Sequence Number: - Start / End Page: 359 - 366 Identifier: ISSN: 0730-725X
CoNE: https://pure.mpg.de/cone/journals/resource/954925533026