English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Mapping Cortical Activity Elicited with Electrical Microstimulation Using fMRI in the Macaque

Tolias, A., Sultan, F., Augath, M., Oeltermann, A., Tehovnik, W., Schiller, P., et al. (2005). Mapping Cortical Activity Elicited with Electrical Microstimulation Using fMRI in the Macaque. Neuron, 48(6), 901-911. doi:10.1016/j.neuron.2005.11.034.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-D36B-F Version Permalink: http://hdl.handle.net/21.11116/0000-0004-D75D-2
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Tolias, AS1, 2, Author              
Sultan , F, Author
Augath, MA1, 2, Author              
Oeltermann, A1, 2, Author              
Tehovnik , WJ, Author
Schiller, PH, Author
Logothetis, NK1, 2, Author              
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

Content

show
hide
Free keywords: -
 Abstract: Over the last two centuries, electrical microstimulation has been used to demonstrate causal links between neural activity and specific behaviors and cognitive functions. However, to establish these links it is imperative to characterize the cortical activity patterns that are elicited by stimulation locally around the electrode and in other functionally connected areas. We have developed a technique to record brain activity using the blood oxygen level dependent (BOLD) signal while applying electrical microstimulation to the primate brain. We find that the spread of activity around the electrode tip in macaque area V1 was larger than expected from calculations based on passive spread of current and therefore may reflect functional spread by way of horizontal connections. Consistent with this functional transynaptic spread we also obtained activation in expected projection sites in extrastriate visual areas, demonstrating the utility of our technique in uncovering in vivo functional connectivity maps.

Details

show
hide
Language(s):
 Dates: 2005-12
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1016/j.neuron.2005.11.034
BibTex Citekey: 4479
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Neuron
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Cambridge, Mass. : Cell Press
Pages: - Volume / Issue: 48 (6) Sequence Number: - Start / End Page: 901 - 911 Identifier: ISSN: 0896-6273
CoNE: https://pure.mpg.de/cone/journals/resource/954925560565