Deutsch
 
Hilfe Datenschutzhinweis Impressum
  DetailsucheBrowse

Datensatz

DATENSATZ AKTIONENEXPORT
  fMRI of Macaque Auditory Cortex in Awake and in Anesthetized Animals

Petkov, C., Kayser, C., Augath, M., Steudel, T., & Logothetis, N. (2005). fMRI of Macaque Auditory Cortex in Awake and in Anesthetized Animals. Poster presented at 35th Annual Meeting of the Society for Neuroscience (Neuroscience 2005), Washington, DC, USA.

Item is

Dateien

einblenden: Dateien
ausblenden: Dateien
:
Neuroscience-2005-Petkov.pdf (beliebiger Volltext), 10MB
Name:
Neuroscience-2005-Petkov.pdf
Beschreibung:
-
OA-Status:
Sichtbarkeit:
Öffentlich
MIME-Typ / Prüfsumme:
application/pdf / [MD5]
Technische Metadaten:
Copyright Datum:
-
Copyright Info:
-
Lizenz:
-

Externe Referenzen

einblenden:
ausblenden:
Beschreibung:
-
OA-Status:

Urheber

einblenden:
ausblenden:
 Urheber:
Petkov, CI1, 2, Autor           
Kayser, C1, 2, Autor           
Augath, M1, 2, Autor           
Steudel, T1, 2, Autor           
Logothetis, NK1, 2, Autor           
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

Inhalt

einblenden:
ausblenden:
Schlagwörter: -
 Zusammenfassung: Functional magnetic resonance imaging (fMRI) with non-human primates is invaluable because localized patterns of activity can guide subsequent neurophysiological recordings. However, it is unknown whether fMRI of the macaque monkey can reveal reliable auditory activations consistent with known properties of primate auditory cortical fields (ACFs). We used high-field (4.7- and 7-Tesla) fMRI to image the blood-oxygen level dependent response (BOLD) of auditory cortex in awake and in anesthetized macaques. For awake-animal imaging we trained a macaque to complete long duration trials of visual fixation in combination with minimal body movement. Scanning this animal at 7T during sound presentation revealed robust activity over auditory cortex in the superior temporal plane. A paradigm where stimulation alternated with image acquisition revealed greater auditory activity than continuous imaging where sound stimulation must compete with the scanner noise. Imaging data with more extensive sound stimulation was obtained from anesthetized animals since these experiments allow for quicker data acquisition. Here, we used sounds varying in center frequency and bandwidth as have neurophysiological experiments mapping the basic organizational properties of macaque ACFs. In the antero-posterior direction, regions within the lateral sulcus were selective for sounds with low and high center frequencies, revealing expected frequency selective gradients (tonotopy) with multiple mirror reversals of these gradients. In comparison to tonal stimulation, sounds with greater spectral bandwidth activated more lateral and medial portions of the superior temporal plane, consistent with this activity occurring over non-primary ACFs. In summary, high-field fMRI reveals the global organization of macaque auditory cortex and will be important for helping us to understand how the primate auditory cortex is functionally organized.

Details

einblenden:
ausblenden:
Sprache(n):
 Datum: 2005-11
 Publikationsstatus: Online veröffentlicht
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: -
 Identifikatoren: BibTex Citekey: 3539
 Art des Abschluß: -

Veranstaltung

einblenden:
ausblenden:
Titel: 35th Annual Meeting of the Society for Neuroscience (Neuroscience 2005)
Veranstaltungsort: Washington, DC, USA
Start-/Enddatum: 2005-11-12 - 2005-11-16

Entscheidung

einblenden:

Projektinformation

einblenden:

Quelle 1

einblenden:
ausblenden:
Titel: 35th Annual Meeting of the Society for Neuroscience (Neuroscience 2005)
Genre der Quelle: Konferenzband
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: -
Seiten: - Band / Heft: - Artikelnummer: 851.5 Start- / Endseite: - Identifikator: -