English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  High-resolution 1H chemical shift imaging in the monkey visual cortex

Juchem, C., Logothetis, N., & Pfeuffer, J. (2005). High-resolution 1H chemical shift imaging in the monkey visual cortex. Magnetic Resonance in Medicine, 54(6), 1541-1546. doi:10.1002/mrm.20687.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-D3F5-A Version Permalink: http://hdl.handle.net/21.11116/0000-0004-D77C-F
Genre: Journal Article

Files

show Files

Locators

show
hide
Description:
-

Creators

show
hide
 Creators:
Juchem, C1, 2, Author              
Logothetis, NK1, 2, Author              
Pfeuffer, J1, 2, Author              
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

Content

show
hide
Free keywords: -
 Abstract: Functionally distinct anatomic subdivisions of the brain can often be only a few millimeters in one or more dimensions. The study of metabolic differences in such structures by means of localized in vivo MR spectroscopy is therefore challenging, if not impossible. In fact, the spatial resolution of chemical shift imaging (CSI) in humans is typically in the range of centimeters. The aim of the present study was to optimize 1 H CSI in monkeys and demonstrate the feasibility of high spatial resolutions up to 1.4 x 2 x 1.4 mm^3. The obtained spatial resolution permitted the segregation of gray and white matter in the visual cortex based on the concentration of different metabolites and neurotransmitters like N-acetylaspartate, glutamate, and creatine. Concentration ratios of white matter versus gray matter tissue as well as between metabolites matched those reported in the literature from healthy human brain, demonstrating the consistency and reliability of the procedure.

Details

show
hide
Language(s):
 Dates: 2005-10
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1002/mrm.20687
BibTex Citekey: 2891
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Magnetic Resonance in Medicine
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: New York : Wiley-Liss
Pages: - Volume / Issue: 54 (6) Sequence Number: - Start / End Page: 1541 - 1546 Identifier: ISSN: 0740-3194
CoNE: https://pure.mpg.de/cone/journals/resource/954925538149