English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Analysis of differential gene expression in healthy and osteoarthritic cartilage and isolated chondrocytes by microarray analysis

Aigner, T., Saas, J., Zien, A., Zimmer, R., Gebhard, P., & Knorr, T. (2004). Analysis of differential gene expression in healthy and osteoarthritic cartilage and isolated chondrocytes by microarray analysis. In M. Sabatini, P. Pastoureau, & F. De Ceuninck (Eds.), Cartilage and Osteoarthritis Volume 1: Cellular and Molecular Tools (pp. 109-128). Totowa, NJ, USA: Humana Press.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-D8AF-B Version Permalink: http://hdl.handle.net/21.11116/0000-0005-53FC-2
Genre: Book Chapter

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Aigner, T, Author
Saas, J, Author
Zien, A1, Author              
Zimmer, R, Author
Gebhard, PM, Author
Knorr, T, Author
Affiliations:
1External Organizations, ou_persistent22              

Content

show
hide
Free keywords: -
 Abstract: The regulation of chondrocytes in osteoarthritic cartilage and the expression of specific gene products by these cells during early-onset and late-stage osteoarthritis are not well characterized. With the introduction of cDNA array technology, the measurement of thousands of different genes in one small tissue sample can be carried out. Interpretation of gene expression analyses in articular cartilage is aided by the fact that this tissue contains only one cell type in both normal and diseased conditions. However, care has to be taken not to over- and misinterpret results, and some major challenges must be overcome in order to utilize the potential of this technology properly in the field of osteoarthritis.

Details

show
hide
Language(s):
 Dates: 2004-07
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: BibTex Citekey: 2834
DOI: 10.1385/1-59259-810-2:109
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Cartilage and Osteoarthritis Volume 1: Cellular and Molecular Tools
Source Genre: Book
 Creator(s):
Sabatini, M, Editor
Pastoureau, P, Editor
De Ceuninck, F, Editor
Affiliations:
-
Publ. Info: Totowa, NJ, USA : Humana Press
Pages: - Volume / Issue: - Sequence Number: - Start / End Page: 109 - 128 Identifier: ISBN: 1-59259-810-2

Source 2

show
hide
Title: Methods in Molecular Medicine
  Other : Methods Mol. Med.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Totowa, N.J. : Humana Press
Pages: - Volume / Issue: 100 Sequence Number: - Start / End Page: - Identifier: ISSN: 1543-1894
CoNE: https://pure.mpg.de/cone/journals/resource/111056645232130