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  Enantioselective oxidation of racemic 1,2-propanediol to D-(−)-lactic acid by Gluconobacter oxydans

Su, W., Chang, Z., Gao, K., & Wei, D. (2004). Enantioselective oxidation of racemic 1,2-propanediol to D-(−)-lactic acid by Gluconobacter oxydans. Tetrahedron: Asymmetry, 15(8), 1275-1277. doi:10.1016/j.tetasy.2004.03.009.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0013-D975-3 Version Permalink: https://hdl.handle.net/21.11116/0000-0005-4F3C-1
Genre: Journal Article

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https://www.sciencedirect.com/science/article/pii/S0957416604001879 (Publisher version)
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 Creators:
Su, W1, Author           
Chang, Z, Author
Gao, K, Author
Wei, D, Author
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1External Organizations, ou_persistent22              

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 Abstract: Gluconobacter oxydans DSM 2003 was firstly used in the production of (R)-2-hydroxy-propionic acid through microbial oxidation of racemic 1,2-propanediol. The biotransformation was processed with high enantiomeric excess (>99) and near theoretical yield (48 of racemic 1,2-propanediol) when the substrate concentration was lower than 20 g/L. When the substrate concentration was increased, maintaining the pH at 6.0 helped to improve the enantioselectivity.

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 Dates: 2004-04
 Publication Status: Issued
 Pages: -
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 Rev. Type: -
 Identifiers: BibTex Citekey: 3211
DOI: 10.1016/j.tetasy.2004.03.009
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Title: Tetrahedron: Asymmetry
Source Genre: Journal
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Publ. Info: Oxford : Pergamon
Pages: - Volume / Issue: 15 (8) Sequence Number: - Start / End Page: 1275 - 1277 Identifier: ISSN: 0957-4166
CoNE: https://pure.mpg.de/cone/journals/resource/954925577039