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  The Negative BOLD Response in Monkey V1 Is Associated with Decreases in Neuronal Activity

Shmuel, A., Augath, M., Oeltermann, A., Pauls, J., Murayama, Y., & Logothetis, N. (2003). The Negative BOLD Response in Monkey V1 Is Associated with Decreases in Neuronal Activity. Poster presented at Ninth Annual Meeting of the Organization for Human Brain Mapping (OHBM 2003), New Orleans, LA, USA.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0013-DC67-B Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0013-DC68-9
Genre: Poster

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 Creators:
Shmuel, A1, Author           
Augath, MA1, Author           
Oeltermann, A2, Author           
Pauls, J1, Author           
Murayama, Y1, Author           
Logothetis, NK1, Author           
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: Negative BOLD responses (NBRs; i.e. below baseline) are pervasive in human fMRI experiments, but commonly ignored. A recent study characterized a robust sustained NBR in the human occipital cortex, triggered by stimulating part of the visual-field (Shmuel et al., 2002). The NBR depends on the pattern of neuronal activity and is coupled to the positive BOLD response (PBR). The NBR is correlated with reductions in cerebral blood flow (CBF) and with decreases in oxygen consumption. The findings from this human study corroborate contributions to the NBR by 1) a significant component of reduction in neuronal activity and possibly 2) a component of hemodynamic changes independent of the local changes in neuronal activity.

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 Dates: 2003-06
 Publication Status: Issued
 Pages: -
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 Rev. Type: -
 Identifiers: URI: http://www.sciencedirect.com/science/article/pii/S1053811905700033
DOI: http://www.sciencedirect.com/science/article/pii/S1053811905700033
BibTex Citekey: 2404
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Title: Ninth Annual Meeting of the Organization for Human Brain Mapping (OHBM 2003)
Place of Event: New Orleans, LA, USA
Start-/End Date: -

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