English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Studying networks of neurons: recordings with multiple, adjustable, chronically-implanted tetrodes in the awake macaque

Tolias, A., Siapas, A., Smirnakis, S., & Logothetis, N. (2001). Studying networks of neurons: recordings with multiple, adjustable, chronically-implanted tetrodes in the awake macaque. In 31st Annual Meeting of the Society for Neuroscience (Neuroscience 2001).

Item is

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Tolias, AS1, 2, Author              
Siapas, AG, Author
Smirnakis, SM1, 2, Author              
Logothetis, NK1, 2, Author              
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

Content

show
hide
Free keywords: -
 Abstract: To date, the neuronal mechanisms of brain processes have been primarily studied by analyzing the activity of neurons recorded one at a time. Further understanding of brain mechanisms is likely to come from studies involving the simultaneous recording of large numbers of single neurons. This has recently become possible with the development of the technique of large-scale chronic tetrode recordings. This technique provides a powerful tool for studying networks of neurons since it allows (a) the reliable isolation of single neuron activity through triangulation of action potentials across the four channels of a tetrode, (b) significant yield, enabling the simultaneous monitoring of large numbers of neurons, and (c) long-term stability of individual neuron recordings over several days, a property critical for studying the neuronal basis of learning. This technique has been successfully used to record the simultaneous activity of on the order of 100 well-isolated neurons in freely behaving rodents (Wilson McNaughton, 1993). We have developed a recording chamber design that allows the chronic implantation of multi-tetrode arrays in awake behaving macaque monkeys. Using this design we have obtained high quality chronic recordings of single neurons from area V1 of a behaving macaque using a 12 tetrode array. These recordings allow the study of how visual information is processed in V1 at the level of networks of single neurons and the investigation of how the interactions across such networks change with learning.

Details

show
hide
Language(s):
 Dates: 2001-11
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: BibTex Citekey: 1057
 Degree: -

Event

show
hide
Title: 31st Annual Meeting of the Society for Neuroscience (Neuroscience 2001)
Place of Event: San Diego, CA, USA
Start-/End Date: 2001-11-10 - 2001-11-15

Legal Case

show

Project information

show

Source 1

show
hide
Title: 31st Annual Meeting of the Society for Neuroscience (Neuroscience 2001)
Source Genre: Proceedings
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: - Sequence Number: 123.5 Start / End Page: - Identifier: -