English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Functional Fields in Human Auditory Cortex Revealed by Time-Resolved fMRI without Interference of EPI Noise

di Salle, F., Formisano, E., Seifritz, E., Linden, D., Scheffler, K., Saulino, C., et al. (2001). Functional Fields in Human Auditory Cortex Revealed by Time-Resolved fMRI without Interference of EPI Noise. NeuroImage, 13(2), 328-338. doi:10.1006/nimg.2000.0683.

Item is

Files

show Files

Locators

show

Creators

show
hide
 Creators:
di Salle, F, Author
Formisano, E, Author
Seifritz, E, Author
Linden, DEJ, Author
Scheffler, K1, Author              
Saulino, C, Author
Tedeschi, G, Author
Zanella, FE, Author
Pepino, A, Author
Goebel, R, Author
Marciano, E, Author
Affiliations:
1External Organizations, ou_persistent22              

Content

show
hide
Free keywords: -
 Abstract: The gradient switching during fast echoplanar functional magnetic resonance imaging (EPI-fMRI) produces loud noises that may interact with the functional activation of the central auditory system induced by experimental acoustic stimuli. This interaction is unpredictable and is likely to confound the interpretation of functional maps of the auditory cortex. In the present study we used an experimental design which does not require the presentation of stimuli during EPI acquisitions and allows for mapping of the auditory cortex without the interference of scanner noise. The design relies on the physiological delays between the onset, or the end, of stimulation and the corresponding hemodynamic response. Owing to these delays and through a time-resolved acquisition protocol it is possible to analyze the decay of the stimulus-specific signal changes after the cessation of the stimulus itself and before the onset of the EPI-acoustic noise related activation (decay-sampling technique). This experimental design, which might permit a more detailed insight in the auditory cortex, has been applied to the study of the cortical responses to pulsed 1000 Hz sine tones. Distinct activation clusters were detected in the Heschl's gyri and the planum temporale, with an increased extension compared to a conventional block-design paradigm. Furthermore, the comparison of the hemodynamic response of the most anterior and the posterior clusters of activation highlighted differential response patterns to the sound stimulation and to the EPI-noise. These differences, attributable to reciprocal saturation effects unevenly distributed over the superior temporal cortex, provided evidence for functionally distinct auditory fields.

Details

show
hide
Language(s):
 Dates: 2001-02
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1006/nimg.2000.0683
BibTex Citekey: DiSalleFSLSSTZPGM2001
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: NeuroImage
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Orlando, FL : Academic Press
Pages: - Volume / Issue: 13 (2) Sequence Number: - Start / End Page: 328 - 338 Identifier: ISSN: 1053-8119
CoNE: https://pure.mpg.de/cone/journals/resource/954922650166