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  Functional imaging of the monkey brain

Logothetis, N., Guggenberger, H., Peled, S., & Pauls, J. (1999). Functional imaging of the monkey brain. Nature Neuroscience, 2(6), 555-562. doi:10.1038/9210.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-E691-B Version Permalink: http://hdl.handle.net/21.11116/0000-0005-BFCD-E
Genre: Journal Article

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https://www.nature.com/articles/nn0699_555.pdf (Publisher version)
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 Creators:
Logothetis, NK1, 2, Author              
Guggenberger, H, Author
Peled, S, Author
Pauls, J1, 2, Author              
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: Functional magnetic resonance imaging (fMRI) has become an essential tool for studying human brain function. Here we describe the application of this technique to anesthetized monkeys. We present spatially resolved functional images of the monkey cortex based on blood oxygenation level dependent (BOLD) contrast. Checkerboard patterns or pictures of primates were used to study stimulus-induced activation of the visual cortex, in a 4.7-Tesla magnetic field, using optimized multi-slice, gradient-recalled, echo-planar imaging (EPI) sequences to image the entire brain. Under our anesthesia protocol, visual stimulation yielded robust, reproducible, focal activation of the lateral geniculate nucleus (LGN), the primary visual area (V1) and a number of extrastriate visual areas, including areas in the superior temporal sulcus. Similar responses were obtained in alert, behaving monkeys performing a discrimination task.

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 Dates: 1999-06
 Publication Status: Published in print
 Pages: -
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 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1038/9210
BibTex Citekey: 204
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Title: Nature Neuroscience
  Other : Nat. Neurosci.
Source Genre: Journal
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Publ. Info: New York, NY : Nature America Inc.
Pages: - Volume / Issue: 2 (6) Sequence Number: - Start / End Page: 555 - 562 Identifier: ISSN: 1097-6256
CoNE: https://pure.mpg.de/cone/journals/resource/954925610931