English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  GABAergic inhibition influences auditory motion-direction sensitivity in barn owls

Kautz, D., & Wagner, H. (1998). GABAergic inhibition influences auditory motion-direction sensitivity in barn owls. Journal of Neurophysiology, 80(1), 172-185. doi:10.1152/jn.1998.80.1.172.

Item is

Files

show Files

Locators

show
hide
Description:
-

Creators

show
hide
 Creators:
Kautz, D1, 2, Author              
Wagner, H1, 2, Author              
Affiliations:
1Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              
2Former Department Comparative Neurobiology, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497800              

Content

show
hide
Free keywords: -
 Abstract: Many neurons in the barn owl's inferior colliculus (IC) exhibit auditory motion-direction sensitivity (MDS), i.e., they respond more to motion of a sound source in one direction than to motion in the opposite direction. We investigated the cellular mechanisms underlying the phenomenon of auditory MDS by microiontophoretically applying gamma-aminobutyric acid (GABA) or the GABA-antagonist bicuculline methiodide (BMI) while recording from neurons in the owl's midbrain. In most cases GABA reduced the overall firing rate, whereas BMI increased it. In addition, 29 of the motion-direction-sensitive cells completely lost their selectivity for the direction of auditory movement during administration of BMI. It had been proposed that auditory MDS in the owl is due to inhibition. The present results show that GABAergic inhibition plays a role in the strengthening of MDS. We discuss the data within the framework of the acoustic motion detector and with respect to microiontophoretic studies on visual motion detection and on inhibitory mechanisms in the inferior colliculus.

Details

show
hide
Language(s):
 Dates: 1998-07
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: BibTex Citekey: 240
DOI: 10.1152/jn.1998.80.1.172
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Journal of Neurophysiology
  Other : J. Neurophysiol.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Bethesda, MD : The Society
Pages: - Volume / Issue: 80 (1) Sequence Number: - Start / End Page: 172 - 185 Identifier: ISSN: 0022-3077
CoNE: https://pure.mpg.de/cone/journals/resource/954925416959