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  Aluminum-27 nuclear magnetic resonance spectroscopy and imaging of the human gastric lumen

Kaspar, A., Bilecen, D., Scheffler, K., & Seelig, J. (1996). Aluminum-27 nuclear magnetic resonance spectroscopy and imaging of the human gastric lumen. Magnetic Resonance in Medicine, 36(2), 177-182. doi:10.1002/mrm.1910360202.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-EB40-E Version Permalink: http://hdl.handle.net/21.11116/0000-0005-E711-3
Genre: Journal Article

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Kaspar, A, Author
Bilecen, D, Author
Scheffler, K1, Author              
Seelig, J, Author
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1External Organizations, ou_persistent22              

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 Abstract: Aluminum NMR is proposed as a new imaging and spectroscopy modality. Its potential is exemplified by in vivo studies of the human stomach. The dissolution kinetics of aluminum-containing drugs at physiological doses and their removal from the human stomach have been followed by 27Al magnetic resonance spectroscopy (MRS). Aluminum concentrations as low as 0.5 mg Al3+ in the human stomach can be detected. The time course of gastric emptying has been visualized with 27Al magnetic resonance imaging (MRI) under normal conditions and in the presence of an antimuscarinic agent, which reduces the gastric motor function. 27Al MRI is the only direct method to visualize the gastric pH. 27Al MRI opens new possibilities for medical and pharmaceutical science.

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 Dates: 1996-08
 Publication Status: Published in print
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 Identifiers: DOI: 10.1002/mrm.1910360202
BibTex Citekey: KasparBSS1996
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Title: Magnetic Resonance in Medicine
Source Genre: Journal
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Publ. Info: New York : Wiley-Liss
Pages: - Volume / Issue: 36 (2) Sequence Number: - Start / End Page: 177 - 182 Identifier: ISSN: 0740-3194
CoNE: https://pure.mpg.de/cone/journals/resource/954925538149