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  Dopaminergic modulation of semantic network activation

Kischka, U., Kammer, T., Weisbrod M, Maier S, Thimm, M., & Spitzer, M. (1996). Dopaminergic modulation of semantic network activation. Neuropsychologia, 34(11), 1107-1113. doi:10.1016/0028-3932(96)00024-3.

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Kischka, U, Author
Kammer, T1, Author           
Weisbrod M, Maier S, Thimm, M, Author
Spitzer, M, Author
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1External Organizations, ou_persistent22              

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 Abstract: In order to examine the effect of dopamine on semantic processing, we performed a double-blind, placebo-controlled study. Healthy volunteers (n = 31) were tested in a lexical decision paradigm after ingestion of either L-dopa 100 mg with benserazide 25 mg or placebo. While direct semantic priming was influenced only marginally by L-dopa, the indirect priming effect was reduced significantly. These data support the hypothesis that dopamine increases the signal-to-noise ratio in semantic networks by reducing the spread of semantic processing, thereby leading to a focussing of activation. Copyright (C) 1996 Elsevier Science Ltd.

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 Dates: 1996-11
 Publication Status: Issued
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 Identifiers: BibTex Citekey: 950
DOI: 10.1016/0028-3932(96)00024-3
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Title: Neuropsychologia
Source Genre: Journal
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Publ. Info: Oxford : Pergamon
Pages: - Volume / Issue: 34 (11) Sequence Number: - Start / End Page: 1107 - 1113 Identifier: ISSN: 0028-3932
CoNE: https://pure.mpg.de/cone/journals/resource/954925428258