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  Small Molecule-Protein Interactions

Waldmann, H., & Koppitz, M. (Eds.). (2003). Small Molecule-Protein Interactions (1.). Berlin [u.a.]: Springer-Verlag.

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 Creators:
Waldmann, Herbert1, Editor           
Koppitz, Marcus, Editor
Affiliations:
1Abt. IV: Chemische Biologie, Max Planck Institute of Molecular Physiology, Max Planck Society, ou_1753290              

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Free keywords: Combinatorial Chemistry, Drug Design, Drug Discovery, Target Assessment, Target Screening
 Abstract: Based on the international workshop on 'Small Molecule - Protein Interactions' held in Berlin, April 24-26, 2002, researchers from industry and academic laboratories describe novel and efficient ways selecting promising new drug targets and developing small molecule inhibitors against them. The structure of the book corresponds to the different aspects of the drug discovery process. All chapters are written by leading experts in the field, who present and discuss the most recent state-of-the-art tools and techniques for the development of novel drugs. The value of the book lies in surveying and summarizing the approaches taken by different companies and institutions giving the reader a balanced view on the use of the latest techniques on the one hand and experience-based assistance in selecting appropriate tools for their own work on the other hand.

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Language(s): eng - English
 Dates: 2003
 Publication Status: Published in print
 Pages: XV, 224 pp.
 Publishing info: Berlin [u.a.] : Springer-Verlag, 1.
 Table of Contents: G. Wess: Drug Discovery Opportunities; A.L. Hopkins / C.R. Groom: Target Analysis: a priori Assessment and Drugability; J. Wells: Site-Directed Drug Discovery at Signaling Interfaces; T. Willson: Chemical Genomics of Orphan Nuclear Receptors; H. Jhoti: High-Throughput X-ray Techniques and Drug Discovery; H. Kessler et al.: NMR in Medicinal Chemistry; M.F.M. Engels: Creating Knowledge from High-Throughput Screening Data; G. Klebe: From Structure to Recognition Principles: Mining in Cystal Data as a Prerequisite for Drug Design; M. Stahl / T. Schulz-Gasch: Practical Database Screening with Docking Tools; H. Briem: De novo Design Methods; R. Breinbauer et al.: From Protein Domains to Drug Candidates - Natural Products as Guiding Principles in Compound Library Design and Synthesis; L. Weber: Discovery of new MCR's, Chemical Evolution and Lead Optimization; P.H.H. Hermkens / G. Müller: The Impact of Combinatorial Chemistry on Drug Discovery.
 Rev. Type: -
 Identifiers: eDoc: 34343
URI: http://www.springer.de/cgi/svcat/search_book.pl?isbn=3-540-43984-6
ISBN: 3-540-43984-6
 Degree: -

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Title: Ernst Schering Research Foundation Workshop
Source Genre: Series
 Creator(s):
Stock, G., Editor
Lessl, M., Editor
Affiliations:
-
Publ. Info: -
Pages: - Volume / Issue: 42 Sequence Number: - Start / End Page: - Identifier: -