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  Identification of an intracellular metabolic signature impairing beta cell function in the rat beta cell line INS-1E and human islets

Goehring, I., Sauter, N. S., Catchpole, G., Assmann, A., Shu, L., Zien, K. S., et al. (2011). Identification of an intracellular metabolic signature impairing beta cell function in the rat beta cell line INS-1E and human islets. Diabetologia, 53(10), 2584-2594. doi:10.1007/s00125-011-2249-7.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0014-21EC-6 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0014-21ED-4
Genre: Meeting Abstract

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 Creators:
Goehring, I.1, Author
Sauter, N. S.1, Author
Catchpole, G.2, Author           
Assmann, A.1, Author
Shu, L.1, Author
Zien, K. S.1, Author
Moehlig, M.1, Author
Pfeiffer, A. F.1, Author
Oberholzer, J.1, Author
Willmitzer, L.2, Author           
Spranger, J.1, Author
Maedler, K.1, Author
Affiliations:
1External Organizations, ou_persistent22              
2Small Molecules, Department Willmitzer, Max Planck Institute of Molecular Plant Physiology, Max Planck Society, ou_1753340              

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Free keywords: Animals Blotting, Western Cell Line Diabetes Mellitus, Type 2/metabolism Gene Expression/drug effects Glucose/pharmacology Humans Insulin-Secreting Cells/drug effects/*metabolism/physiology Islets of Langerhans/drug effects/*metabolism/*physiopathology Mass Spectrometry Mitogen-Activated Protein Kinase 1/metabolism Mitogen-Activated Protein Kinase 3/metabolism Pentose Phosphate Pathway/physiology Phosphogluconate Dehydrogenase/metabolism Rats
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Language(s): eng - English
 Dates: 2011-07-292011
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: ISI: ISI:000280689700069
DOI: 10.1007/s00125-011-2249-7
ISSN: 1432-0428 (Electronic) 0012-186X (Linking)
URI: ://000280689700069
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Title: Diabetologia
Source Genre: Journal
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Pages: - Volume / Issue: 53 (10) Sequence Number: - Start / End Page: 2584 - 2594 Identifier: -