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Schlagwörter:
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Zusammenfassung:
A new efficient synthesis of 1-deoxy-l-xylulose (1) is presented. The key step is achieved by a highly enantioselective aldol addition of hydroxyacetone to benzyloxyacetaldehyde via antibody catalysis. The synthesis described here should provide a convenient route to isotopically labeled derivatives.
A two step enantioselective synthesis of 1-deoxy-L-xylulose has been achieved utilizing aldolase antibody 38C2 (Aldrich #47,995-0)
