ausblenden:
Schlagwörter:
acylcyanation; asymmetric catalysis; organocatalysis; Strecker reaction; thiourea
Zusammenfassung:
The less problematic acetyl cyanide can be used instead of toxic HCN for the highly enantioselective acyl‐Strecker‐type reaction. In the presence of an N‐benzylimine and a catalytic amount of Jacobsen's catalyst 1, the desired α‐amidonitrile is obtained in excellent enantioselectivity and yield.
