English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
 
 
DownloadE-Mail
  BigBrain: An ultrahigh-resolution 3D human brain model

Amunts, K., Lepage, C., Borgeat, L., Mohlberg, H., Dickscheid, T., Rousseau, M.-É., et al. (2013). BigBrain: An ultrahigh-resolution 3D human brain model. Science, 340(6139), 1472-1475. doi:10.1126/science.1235381.

Item is

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Amunts, Katrin1, 2, 3, 4, Author
Lepage, Claude5, Author
Borgeat, Louis6, Author
Mohlberg, Hartmut1, 2, Author
Dickscheid, Timo1, 2, Author
Rousseau, Marc-Étienne5, Author
Bludau, Sebastian1, 2, Author
Bazin, Pierre-Louis7, 8, Author           
Lewis, Lindsay B.5, Author
Oros-Peusquens, Ana-Maria1, 2, Author
Shah, Nadim J.1, 2, Author
Lippert, Thomas9, Author
Zilles, Karl1, 2, 3, 4, Author
Evans, Alan C.5, Author
Affiliations:
1Institute of Neuroscience and Medicine, Research Center Jülich, Germany, ou_persistent22              
2Jülich Aachen Research Alliance - JARA BRAIN, Jülich, Germany, ou_persistent22              
3Department of Psychiatry, Psychotherapy, and Psychosomatics, RWTH Aachen University, Germany, ou_persistent22              
4C. and O. Vogt Institute for Brain Research, Heinrich Heine University Düsseldorf, Germany, ou_persistent22              
5Montreal Neurological Institute and Hospital, McGill University, Montréal, QC, Canada, ou_persistent22              
6National Research Council of Canada, Ottawa, ON, Canada, ou_persistent22              
7Department Neurophysics, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634550              
8Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, Leipzig, DE, ou_634549              
9Supercomputing Centre, Research Center Jülich, Germany, ou_persistent22              

Content

show
hide
Free keywords: -
 Abstract: Reference brains are indispensable tools in human brain mapping, enabling integration of multimodal data into an anatomically realistic standard space. Available reference brains, however, are restricted to the macroscopic scale and do not provide information on the functionally important microscopic dimension. We created an ultrahigh-resolution three-dimensional (3D) model of a human brain at nearly cellular resolution of 20 micrometers, based on the reconstruction of 7404 histological sections. “BigBrain” is a free, publicly available tool that provides considerable neuroanatomical insight into the human brain, thereby allowing the extraction of microscopic data for modeling and simulation. BigBrain enables testing of hypotheses on optimal path lengths between interconnected cortical regions or on spatial organization of genetic patterning, redefining the traditional neuroanatomy maps such as those of Brodmann and von Economo.

Details

show
hide
Language(s): eng - English
 Dates: 2013-01-212013-05-152013-06-21
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1126/science.1235381
PMID: 23788795
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Science
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Washington, D.C. : American Association for the Advancement of Science
Pages: - Volume / Issue: 340 (6139) Sequence Number: - Start / End Page: 1472 - 1475 Identifier: ISSN: 0036-8075
CoNE: https://pure.mpg.de/cone/journals/resource/991042748276600_1