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  True real-time cardiac MRI in free breathing without ECG synchronization using a novel sequence with radial k-space sampling and balanced SSFP contrast mode.

Bauer, R. W., Radtke, I., Block, K. T., Larson, M. C., Kerl, J. M., Hammerstingl, R., et al. (2013). True real-time cardiac MRI in free breathing without ECG synchronization using a novel sequence with radial k-space sampling and balanced SSFP contrast mode. The International Journal of Cardiovascular Imaging, 29(5), 1059-1067. doi:10.1007/s10554-013-0183-0.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0014-3EC3-A Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0027-CA50-4
Genre: Journal Article

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1833516.pdf (Publisher version), 435KB
 
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 Creators:
Bauer, R. W., Author
Radtke, I., Author
Block, K. T., Author
Larson, M. C., Author
Kerl, J. M., Author
Hammerstingl, R., Author
Graf, T. G., Author
Vogl, T. J., Author
Zhang, S.1, Author              
Affiliations:
1Biomedical NMR Research GmbH, MPI for biophysical chemistry, Max Planck Society, ou_578634              

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Free keywords: Real-time MRI; Cardiac MRI; Radial sampling; Cardiac function
 Abstract: We investigated a novel sequence with radial k-space sampling, gridding and sliding window reconstruction with bSSFP contrast that allows for true real-time functional cardiac evaluation independent from respiration and ECG triggering. 12 healthy volunteers underwent 1.5 T cardiac MRI. Single-shot short axis views were acquired with a) standard retrospectively ECG-gated segmented breath-hold (bh) bSSFP and with the real-time radial bSSFP sequence with a nominal temporal resolution of b) 16 fps (frames per second) and c) 40 fps. Radial bSSFP were acquired during free breathing without ECG synchronization. Left ventricular functional parameters (EDV, ESV, SV and EF) were compared and quality of wall motion depiction was assessed. Contrast-to-noise-ratio (CNR) of myocardium/blood pool in the left ventricle was calculated. EF showed excellent correlation (Bland-Altman r = 0.99; Lin rho = 0.91) between bh-bSSFP (65 %) and 40 fps radial (64 %) and moderate correlation (r = 0.84, rho = 0.20) with 16 fps radial bSSFP (56 %). While EDV was in good agreement for all three sequences, ESV was significantly overestimated with 16 fps radial bSSFP. Despite lower CNR, image quality for wall motion assessment was rated significantly better for 40 fps compared to 16 fps radial bSSFP due to the faster temporal resolution. Left ventricular functional analysis with fast true real-time radial bSSFP is in good agreement with standard ECG-gated bh-bSSFP. The independency from ECG synchronization and breathing promises a robust method for patients with impaired cardiopulmonary status in whom breath-hold and good quality ECG cannot be achieved.

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Language(s): eng - English
 Dates: 2013-01-192013-06
 Publication Status: Published in print
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 Rev. Method: Peer
 Identifiers: DOI: 10.1007/s10554-013-0183-0
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Title: The International Journal of Cardiovascular Imaging
Source Genre: Journal
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Pages: - Volume / Issue: 29 (5) Sequence Number: - Start / End Page: 1059 - 1067 Identifier: -