English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Facilitation of inferior frontal cortex by transcranial direct current stimulation induces perceptual learning of severely degraded speech

Sehm, B., Schnitzler, T., Obleser, J., Groba, A., Ragert, P., Villringer, A., et al. (2013). Facilitation of inferior frontal cortex by transcranial direct current stimulation induces perceptual learning of severely degraded speech. The Journal of Neuroscience, 33(40), 15868-15878. doi:10.1523/JNEUROSCI.5466-12.2013.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0014-4CC7-2 Version Permalink: http://hdl.handle.net/21.11116/0000-0003-5048-2
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Sehm, Bernhard1, 2, Author              
Schnitzler, Tim1, Author
Obleser, Jonas3, Author              
Groba, Agnes1, 4, Author              
Ragert, Patrick1, Author              
Villringer, Arno1, 2, Author              
Obrig, Hellmuth1, 2, Author              
Affiliations:
1Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
2Clinic for Cognitive Neurology, University of Leipzig, Germany, ou_persistent22              
3Max Planck Research Group Auditory Cognition, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_751545              
4Department of Linguistics, University of Erfurt, Germany, ou_persistent22              

Content

show
hide
Free keywords: -
 Abstract: Perceptual learning requires the generalization of categorical perceptual sensitivity from trained to untrained items. For degraded speech, perceptual learning modulates activation in a left-lateralized network, including inferior frontal gyrus (IFG) and inferior parietal cortex (IPC). Here we demonstrate that facilitatory anodal transcranial direct current stimulation (tDCSanodal) can induce perceptual learning in healthy humans. In a sham-controlled, parallel design study, 36 volunteers were allocated to the three following intervention groups: tDCSanodal over left IFG, IPC, or sham. Participants decided on the match between an acoustically degraded and an undegraded written word by forced same-different choice. Acoustic degradation varied in four noise-vocoding levels (2, 3, 4, and 6 bands). Participants were trained to discriminate between minimal (/Tisch/-FISCH) and identical word pairs (/Tisch/-TISCH) over a period of 3 d, and tDCSanodal was applied during the first 20 min of training. Perceptual sensitivity (d′) for trained word pairs, and an equal number of untrained word pairs, was tested before and after training. Increases in d′ indicate perceptual learning for untrained word pairs, and a combination of item-specific and perceptual learning for trained word pairs. Most notably for the lowest intelligibility level, perceptual learning occurred only when tDCSanodal was applied over left IFG. For trained pairs, improved d′ was seen on all intelligibility levels regardless of tDCS intervention. Over left IPC, tDCSanodal did not modulate learning but instead introduced a response bias during training. Volunteers were more likely to respond “same,” potentially indicating enhanced perceptual fusion of degraded auditory with undegraded written input. Our results supply first evidence that neural facilitation of higher-order language areas can induce perceptual learning of severely degraded speech.

Details

show
hide
Language(s): eng - English
 Dates: 20132013-10-02
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1523/JNEUROSCI.5466-12.2013
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: The Journal of Neuroscience
  Other : J. Neurosci.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Baltimore, MD : The Society
Pages: - Volume / Issue: 33 (40) Sequence Number: - Start / End Page: 15868 - 15878 Identifier: ISSN: 0270-6474
CoNE: /journals/resource/954925502187_1