ausblenden:
Schlagwörter:
lepidoptera
noctuidae
agrotis segetum
(z)-5-decenyl acetate
pheromone analog
halides
structure-activity
single-sensillum
recordings
receptor-interaction
agrotis-segetum
turnip moth
receptor
lepidoptera
analogs
Zusammenfassung:
Analogs of (Z)-5-decenyl acetate, a pheromone component of the turnip moth, Agrotis segetum, with a chloro, bromo, or iodo substituent in place of the terminal methyl group have been synthesized and tested by electrophysiological single-sensillum recordings. The electrophysiological results have been interpreted in terms of substituent size and hydrophobicity. Interaction energies based on receptor interaction models have been calculated using the molecular mechanics [MM2(85)] method. The results support our previously suggested receptor interaction model in which the terminal alkyl chain interact with a complementary hydrophobic receptor "pocket" with very limited flexibility.
