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  Enriched environment at work and the incidence of dementia: Results of the Leipzig Longitudinal Study of the Aged (LEILA 75+)

Then, F. S., Luppa, M., Schroeter, M. L., König, H.-H., Angermeyer, M. C., & Riedel-Heller, S. G. (2013). Enriched environment at work and the incidence of dementia: Results of the Leipzig Longitudinal Study of the Aged (LEILA 75+). PLoS One, 8(7): e70906. doi:10.1371/journal.pone.0070906.

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Genre: Zeitschriftenartikel

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Then_EnrichedEnvironment.pdf (Verlagsversion), 299KB
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2013
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© 2013 Then et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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 Urheber:
Then, Francisca S.1, 2, Autor
Luppa, Melanie1, Autor
Schroeter, Matthias L.2, 3, Autor           
König, Hans-Helmut4, Autor
Angermeyer, Matthias C.5, 6, Autor
Riedel-Heller, Steffi G.1, Autor
Affiliations:
1Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig, Germany, ou_persistent22              
2LIFE – Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany, ou_persistent22              
3Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
4Department of Medical Sociology and Health Economics, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany, ou_persistent22              
5Center for Public Mental Health, Gösing am Wagram, Austria, ou_persistent22              
6Department of Public Health, University of Cagliary, Cagliary, Italy, ou_persistent22              

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 Zusammenfassung: Background

The high incidence of cognitive impairments in the aging population together with the challenges it imposes on health systems raise the question of what effect working life has on cognitive abilities. Animal models have demonstrated that so called enriched environments protect against neurodegenerative diseases, such as dementia. The aim was to investigate the impact of enriched environment at work on the incidence of dementia.
Methods

The Leipzig Longitudinal Study of the Aged (LEILA 75+) is an ongoing representative population cohort study that examines cognitive functioning and dementia in individuals aged 75 years and older. The participants’ occupational information was matched to O*NET SOC codes and the relevant job descriptors were used to create occupational context indices describing enriched environment at work.
Results

Results of logistic regression modeling suggest that a higher level of the index Executive was associated with a lower risk of incident dementia (odds ratio = 0.61, 95% confidence interval = 0.47–0.79, p<0.001). Adjustment for various confounders did not alter the association. The cognitive stimulation indices were only significant in univariate analysis. The Novelty-index remained non-significant.
Conclusions

The results suggest that occupational contexts enriched with independent planning/performance of work tasks might decrease the risk of developing dementia. A protective effect of enriched environment at work in general, namely high cognitive stimulation or confrontation with new tasks, could not be confirmed by the results.

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Sprache(n): eng - English
 Datum: 2013-02-212013-06-242013-07-26
 Publikationsstatus: Online veröffentlicht
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: DOI: 10.1371/journal.pone.0070906
PMID: 23923030
PMC: PMC3724805
Anderer: Print 2013
 Art des Abschluß: -

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Titel: PLoS One
Genre der Quelle: Zeitschrift
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Affiliations:
Ort, Verlag, Ausgabe: San Francisco, CA : Public Library of Science
Seiten: - Band / Heft: 8 (7) Artikelnummer: e70906 Start- / Endseite: - Identifikator: ISSN: 1932-6203
CoNE: https://pure.mpg.de/cone/journals/resource/1000000000277850