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  Histone Deacetylase Inhibition Enhances Self Renewal and Cardioprotection by Human Cord Blood-Derived CD34+ Cells

Burba, I., Colombo, G. I., Staszewsky, L. I., De Simone, M., Devanna, P., Nanni, S., et al. (2011). Histone Deacetylase Inhibition Enhances Self Renewal and Cardioprotection by Human Cord Blood-Derived CD34+ Cells. PLoS One, 6(7): e22158. doi:10.1371/journal.pone.0022158.

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2011
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Copyright: © 2011 Burba et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Burba, Ilaria, Author
Colombo, Gualtiero I., Author
Staszewsky, Lidia Irene, Author
De Simone, Marco , Author
Devanna, Paolo1, 2, Author           
Nanni, Simona, Author
Avitabile, Daniele, Author
Molla, Fabiola, Author
Cosentino, Simona, Author
Russo, Ilaria, Author
De Angelis, Noeleen, Author
Soldo, Annarita, Author
Biondi, Antonella, Author
Gambini, Elisa, Author
Gaetano, Carlo, Author
Farsetti, Antonella, Author
Pompilio, Giulio, Author
Latini, Roberto, Author
Capogrossi, Maurizio C., Author
Pesce, Maurizio, Author
Affiliations:
1Language and Genetics Department, MPI for Psycholinguistics, Max Planck Society, ou_792549              
2Laboratorio di Biologia Vascolare e Medicina Rigenerativa, Centro Cardiologico Monzino, IRCCS, Milan, Italy, ou_persistent22              

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 Abstract: Use of peripheral blood- or bone marrow-derived progenitors for ischemic heart repair is a feasible option to induce neo-vascularization in ischemic tissues. These cells, named Endothelial Progenitors Cells (EPCs), have been extensively characterized phenotypically and functionally. The clinical efficacy of cardiac repair by EPCs cells remains, however, limited, due to cell autonomous defects as a consequence of risk factors. The devise of “enhancement” strategies has been therefore sought to improve repair ability of these cells and increase the clinical benefit

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Language(s): eng - English
 Dates: 2011
 Publication Status: Published online
 Pages: -
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 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1371/journal.pone.0022158
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Title: PLoS One
Source Genre: Journal
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Publ. Info: San Francisco, CA : Public Library of Science
Pages: - Volume / Issue: 6 (7) Sequence Number: e22158 Start / End Page: - Identifier: ISSN: 1932-6203
CoNE: https://pure.mpg.de/cone/journals/resource/1000000000277850