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  Real-time cardiovascular magnetic resonance at 1.5 T using balanced SSFP and 40 ms resolution.

Voit, D., Zhang, S., Unterberg-Buchwald, C., Sohns, J. M., Lotz, J., & Frahm, J. (2013). Real-time cardiovascular magnetic resonance at 1.5 T using balanced SSFP and 40 ms resolution. Journal of Cardiovascular Magnetic Resonance, 15(1): 79. doi:10.1186/1532-429X-15-79.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0014-62D9-B Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0028-2AC1-C
Genre: Journal Article

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Voit, D.1, Author              
Zhang, S.1, Author              
Unterberg-Buchwald, C., Author
Sohns, J. M., Author
Lotz, J., Author
Frahm, J.1, Author              
Affiliations:
1Biomedical NMR Research GmbH, MPI for biophysical chemistry, Max Planck Society, ou_578634              

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Free keywords: Real-time CMR; Cardiovascular magnetic resonance; SSFP; Arrhythmias; Abnormal wall motion
 Abstract: Background: While cardiovascular magnetic resonance (CMR) commonly employs ECG-synchronized cine acquisitions with balanced steady-state free precession (SSFP) contrast at 1.5 T, recent developments at 3 T demonstrate significant potential for T1-weighted real-time imaging at high spatiotemporal resolution using undersampled radial FLASH. The purpose of this work was to combine both ideas and to evaluate a corresponding real-time CMR method at 1.5 T with SSFP contrast. Methods: Radial gradient-echo sequences with fully balanced gradients and at least 15-fold undersampling were implemented on two CMR systems with different gradient performance. Image reconstruction by regularized nonlinear inversion (NLINV) was performed offline and resulted in real-time SSFP CMR images at a nominal resolution of 1.8 mm and with acquisition times of 40 ms. Results: Studies of healthy subjects demonstrated technical feasibility in terms of robustness and general image quality. Clinical applicability with access to quantitative evaluations (e.g., ejection fraction) was confirmed by preliminary applications to 27 patients with typical indications for CMR including arrhythmias and abnormal wall motion. Real-time image quality was slightly lower than for cine SSFP recordings, but considered diagnostic in all cases. Conclusions: Extending conventional cine approaches, real-time radial SSFP CMR with NLINV reconstruction provides access to individual cardiac cycles and allows for studies of patients with irregular heartbeat.

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Language(s): eng - English
 Dates: 2013-09-12
 Publication Status: Published online
 Pages: -
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 Rev. Method: Peer
 Identifiers: DOI: 10.1186/1532-429X-15-79
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Title: Journal of Cardiovascular Magnetic Resonance
Source Genre: Journal
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Pages: 8 Volume / Issue: 15 (1) Sequence Number: 79 Start / End Page: - Identifier: -