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  Anatomical brain imaging at 7T using two-dimensional GRASE

Trampel, R., Reimer, E., Huber, L., Ivanov, D., Heidemann, R. M., Schäfer, A., et al. (2014). Anatomical brain imaging at 7T using two-dimensional GRASE. Magnetic Resonance in Medicine, 72(5), 1291-1301. doi:10.1002/mrm.25047.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0014-73C3-5 Version Permalink: http://hdl.handle.net/21.11116/0000-0003-7E9F-E
Genre: Journal Article

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 Creators:
Trampel, Robert1, Author              
Reimer, Enrico1, Author              
Huber, Laurentius1, 2, Author              
Ivanov, Dimo1, 3, Author              
Heidemann, Robin M.1, 4, Author              
Schäfer, Andreas1, Author              
Turner, Robert1, Author              
Affiliations:
1Department Neurophysics, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634550              
2Methods and Development Unit Nuclear Magnetic Resonance, MPI for Human Cognitive and Brain Sciences, Max Planck Society, Leipzig, DE, ou_634558              
3Maastricht University, The Netherlands, ou_persistent22              
4Siemens AG, Erlangen, Germany, ou_persistent22              

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Free keywords: GRASE; structural imaging; brain; high resolution; 7 Tesla; SAR
 Abstract: Purpose: Specific absorption rate is a serious problem at high field strengths, especially for sequences involving many high power radiofrequency pulses, such as turbo spin echo (TSE). GRASE (gradient and spin echo) may overcome this problem by omitting a certain number of refocusing pulses of a TSE sequence, and replacing them with segmented echo-planar imaging readouts. Methods: GRASE and TSE were compared using similar sequence parameters at a field strength of 7T. The signal-to-noise ratio (SNR) per unit time, contrast, and point spread function (PSF) were determined. High-resolution human brain images were acquired and the implementation of an inversion recovery preparation for T1 weighting was evaluated. Results: TSE and GRASE images at 7T showed very similar SNR and contrast. The slightly worse PSF for GRASE is balanced by a significant reduction in scan time or increase in spatial coverage compared with TSE. Furthermore, implementing an additional inversion recovery preparation enables the acquisition of T1-weighted images with high SNR per unit time. Conclusion: GRASE is highly suitable for structural scanning at ultra-high field strengths and is a valid alternative to the commonly used TSE sequence.

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Language(s): eng - English
 Dates: 2013-10-252013-05-292013-10-242013-12-172014-11
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1002/mrm.25047
PMID: 24443053
Other: Epub 2013
 Degree: -

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Title: Magnetic Resonance in Medicine
Source Genre: Journal
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Publ. Info: New York : Wiley-Liss
Pages: - Volume / Issue: 72 (5) Sequence Number: - Start / End Page: 1291 - 1301 Identifier: ISSN: 0740-3194
CoNE: https://pure.mpg.de/cone/journals/resource/954925538149