English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Lotka–Volterra dynamics kills the Red Queen: population size fluctuations and associated stochasticity dramatically change host-parasite coevolution

Gokhale, C. S., Papkou, A., Traulsen, A., & Schulenburg, H. (2013). Lotka–Volterra dynamics kills the Red Queen: population size fluctuations and associated stochasticity dramatically change host-parasite coevolution. BMC Evolutionary Biology, 13(1): 254. doi:10.1186/1471-2148-13-254.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0014-BC2F-B Version Permalink: http://hdl.handle.net/21.11116/0000-0003-D5C1-2
Genre: Journal Article

Files

show Files
hide Files
:
Gokhale_2013.pdf (Publisher version), 2MB
Name:
Gokhale_2013.pdf
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show

Creators

show
hide
 Creators:
Gokhale, Chaitanya S.1, Author              
Papkou, Andrei, Author
Traulsen, Arne1, Author              
Schulenburg, Hinrich2, Author              
Affiliations:
1Research Group Evolutionary Theory, Max Planck Institute for Evolutionary Biology, Max Planck Society, ou_1445641              
2External Organizations, ou_persistent22              

Content

show
hide
Free keywords: host-parasite coevolution; Red Queen hypothesis; Lotka-Volterra dynamics; genetic drift; population bottleneck
 Abstract: Background: Host-parasite coevolution is generally believed to follow Red Queen dynamics consisting of ongoing oscillations in the frequencies of interacting host and parasite alleles. This belief is founded on previous theoretical work, which assumes infinite or constant population size. To what extent are such sustained oscillations realistic? Results: Here, we use a related mathematical modeling approach to demonstrate that ongoing Red Queen dynamics is unlikely. In fact, they collapse rapidly when two critical pieces of realism are acknowledged: (i) population size fluctuations, caused by the antagonism of the interaction in concordance with the Lotka-Volterra relationship; and (ii) stochasticity, acting in any finite population. Together, these two factors cause fast allele fixation. Fixation is not restricted to common alleles, as expected from drift, but also seen for originally rare alleles under a wide parameter space, potentially facilitating spread of novel variants. Conclusion: Our results call for a paradigm shift in our understanding of host-parasite coevolution, strongly suggesting that these are driven by recurrent selective sweeps rather than continuous allele oscillations.

Details

show
hide
Language(s): eng - English
 Dates: 2013-08-082013-11-132013-11-19
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1186/1471-2148-13-254
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: BMC Evolutionary Biology
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: BioMed Central
Pages: - Volume / Issue: 13 (1) Sequence Number: 254 Start / End Page: - Identifier: ISSN: 1471-2148
CoNE: /journals/resource/111000136905006