ausblenden:
Schlagwörter:
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Zusammenfassung:
We provide here a molecular movie that captures key aspects of RNA polymerase II initiation and
elongation. To create the movie, we combined structural snapshots of the initiation-elongation
transition and of elongation, including nucleotide addition, translocation, pausing, proofreading,
backtracking, arrest, reactivation, and inhibition. The movie reveals open questions about the
mechanism of transcription and provides a useful teaching tool.
