English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Contralateral prefrontal projections in gerbils mature abnormally after early methamphetamine trauma and isolated rearing

Witte, V., Bagorda, F., Teuchert-Noodt, G., & Lehmann, K. (2007). Contralateral prefrontal projections in gerbils mature abnormally after early methamphetamine trauma and isolated rearing. Journal of Neural Transmission, 114(2), 285-288. doi:10.1007/s00702-006-0506-6.

Item is

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Witte, Veronica1, Author           
Bagorda, F.1, Author
Teuchert-Noodt, G.1, Author
Lehmann, K.2, Author
Affiliations:
1Department of Neuroanatomy, Faculty of Biology, University of Bielefeld, Germany, ou_persistent22              
2Department of Neurobiology, Institute of General Zoology, Friedrich Schiller University Jena, Germany, ou_persistent22              

Content

show
hide
Free keywords: Methamphetamine; Prefrontal cortex; Dysconnection; Laterality; Cortico-cortical projections
 Abstract: As previously shown, a miswiring of ipsilateral prefrontal projections after methamphetamine (MA) intoxication and/or isolated rearing (IR) may serve as a model of so-called “dysconnection” in human schizophrenia. We here find that deep prefrontal projections to contralateral targets were drastically reduced by both MA and IR alone, but remained equally dense if both impairments cumulated. Projections from superficial layers were not altered by MA and/or IR. These findings confirm that the normal intercortical integration of information is compromised in this animal model of schizophrenia.

Details

show
hide
Language(s): eng - English
 Dates: 2007-02
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1007/s00702-006-0506-6
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Journal of Neural Transmission
  Other : J. Neural Transm.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Wien : Springer-Verlag.
Pages: - Volume / Issue: 114 (2) Sequence Number: - Start / End Page: 285 - 288 Identifier: ISSN: 0300-9564
CoNE: https://pure.mpg.de/cone/journals/resource/991042725899232