ausblenden:
Schlagwörter:
Enzymic reactions; Allosteric regulation; Diffusion; Synchronization;
Microvolumes
Zusammenfassung:
Strong diffusional mixing and short delivery times typical for micrometer and sub-micrometer reaction volumes lead to a special situation where the turnover times of individual enzyme molecules become the largest characteristic time scale of the chemical kinetics. Under these conditions, populations of cross-regulating allosteric enzymes form molecular networks that exhibit various kinds of self-organized coherent collective dynamics.