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  Mechanisms shaping glutamate-mediated excitatory postsynaptic currents in the CNS

Jonas, P., & Spruston, N. (1994). Mechanisms shaping glutamate-mediated excitatory postsynaptic currents in the CNS. Current Opinion in Neurobiology, 4(3), 366-372. doi:10.1016/0959-4388(94)90098-1.

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CurrOpinNeurobiol_4_1994_366.pdf (Any fulltext), 951KB
 
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Jonas, Peter1, Author           
Spruston, Nelson1, Author           
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1Department of Cell Physiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497701              

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 Abstract: Excitatory postsynaptic currents in neurones of the central nervous system have a dual-component time course that results from the co-activation of AMPA/kainate-type and NMDA-type glutamate receptors. New approaches in electrophysiology and molecular biology have provided a better understanding of the factors that determine the kinetics of excitatory postsynaptic currents. Recent studies suggest that the time course of neurotransmitter concentration in the synaptic cleft, the gating properties of the native channels, and the glutamate receptor subunit composition all appear to be important factors.

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Language(s): eng - English
 Dates: 1994-06-01
 Publication Status: Issued
 Pages: 7
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 Table of Contents: -
 Rev. Type: Peer
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Title: Current Opinion in Neurobiology
  Other : Curr. Opin.Neurobiol.
Source Genre: Journal
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Publ. Info: New York, NY : Elsevier Current Trends
Pages: - Volume / Issue: 4 (3) Sequence Number: - Start / End Page: 366 - 372 Identifier: ISSN: 0959-4388
CoNE: https://pure.mpg.de/cone/journals/resource/954925578066