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  Studying block in cloned N-methyl--aspartate (NMDA) receptors

Ruppersberg, J. P., Mosbacher, J., Günther, W., Schöpfer, R., & Fakler, B. (1993). Studying block in cloned N-methyl--aspartate (NMDA) receptors. Biochemical Pharmacology, 46(11), 1877-1885. doi:10.1016/0006-2952(93)90627-9.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0019-A9EB-5 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-002D-24A3-A
Genre: Journal Article
Alternative Title : Commentary Studying block in cloned N-methyl--aspartate (NMDA) receptors

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BiochemPharmacol_46_1993_1877.pdf (Any fulltext), 735KB
 
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 Creators:
Ruppersberg, J. Peter1, Author           
Mosbacher, Johannes1, Author           
Günther, Willy1, Author           
Schöpfer, Ralf2, Author           
Fakler, Bernd3, Author           
Affiliations:
1Department of Cell Physiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497701              
2Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497704              
3Max Planck Institute for Medical Research, Max Planck Society, ou_1125545              

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 Abstract: The biophysics of block of NMDA receptor channels has been investigated extensively during the past 8 years. In the last few years, cloned NMDA receptor channels have become available. Here we have discussed advantages and disadvantages of studying block phenomena in cloned NMDA receptors. Some recent work on the pore block of the cloned NMDA receptor channels was critically reviewed and extended by data about the calcium block. Novel effects of kainate on cloned NMDA receptors and of NMDA on cloned AMPA receptors were reported and discussed with respect to recent work concerning possible occurrence of NMDA-AMPA hybrid channels.

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Language(s): eng - English
 Dates: 1993-12-03
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: eDoc: 666817
DOI: 10.1016/0006-2952(93)90627-9
URI: https://www.ncbi.nlm.nih.gov/pubmed/8267638
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Title: Biochemical Pharmacology
Source Genre: Journal
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Publ. Info: Amsterdam, Boston : Elsevier
Pages: - Volume / Issue: 46 (11) Sequence Number: - Start / End Page: 1877 - 1885 Identifier: ISSN: 0006-2952
CoNE: https://pure.mpg.de/cone/journals/resource/954925384102