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  The rat delta-1 and delta-2 subunits extend the excitatory amino acid receptor family

Lomeli, H., Sprengel, R., Laurie, D. J., Köhr, G., Herb, A., Seeburg, P. H., et al. (1993). The rat delta-1 and delta-2 subunits extend the excitatory amino acid receptor family. FEBS Letters, 315(3), 318-322. doi:10.1016/0014-5793(93)81186-4.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0019-AA9B-6 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002D-1DB7-2
Genre: Journal Article
Alternative Title : The rat delta-1 and delta-2 subunits extend the excitatory amino acid receptor family

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FEBSLett_315_1993_318.pdf (Any fulltext), 737KB
 
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 Creators:
Lomeli, Hilda, Author
Sprengel, Rolf1, Author              
Laurie, David J., Author
Köhr, Georg1, Author              
Herb, Anne1, Author              
Seeburg, Peter H.1, Author              
Wisden, William, Author
Affiliations:
1Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497704              

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Free keywords: Glutamate receptor; Rat brain; Purkinje cell
 Abstract: We have characterized a second member (delta-2) of a new class of subunits for the ligand-gated excitatory amino acid receptor superfamily. The sequence of delta-2 exhibits an average identity of 25% and 18.5% to the non-NMDA and NMDA receptor subunits, respectively. The rat delta-2 gene is expressed predominantly in Purkinje cells of the cerebellum whereas only low levels of delta-1 transcripts are found in the adult brain. However, delta-1 gene expression undergoes a pronounced developmental peak, with particularly high mRNA levels in the caudate putamen of late embryonic/early postnatal stages.

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Language(s): eng - English
 Dates: 1992-10-232001-11-141993-01-11
 Publication Status: Published in print
 Pages: 5
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Degree: -

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Title: FEBS Letters
  Other : FEBS Lett.
Source Genre: Journal
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Publ. Info: Amsterdam : Elsevier
Pages: - Volume / Issue: 315 (3) Sequence Number: - Start / End Page: 318 - 322 Identifier: ISSN: 0014-5793
CoNE: https://pure.mpg.de/cone/journals/resource/954925399501