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  Glutamate-gated ion channels in the brain. Genetic mechanism for generating molecular and functional diversity

Sommer, B., Monyer, H., Wisden, W., Verdoorn, T. A., Burnashev, N., Sprengel, R., et al. (1992). Glutamate-gated ion channels in the brain. Genetic mechanism for generating molecular and functional diversity. Arzneimittel−Forschung, 42(2A), 209-210. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/1375026.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0019-ABAA-B Version Permalink: http://hdl.handle.net/21.11116/0000-0000-606B-C
Genre: Journal Article

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ArzneimittForsch_42_1992_209.pdf (Any fulltext), 3MB
 
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 Creators:
Sommer, Bernd, Author
Monyer, Hannah1, Author              
Wisden, William, Author
Verdoorn, Todd A., Author
Burnashev, Nail2, Author              
Sprengel, Rolf1, 3, 4, Author              
Sakmann, Bert2, Author              
Seeburg, Peter H.5, Author              
Affiliations:
1Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497704              
2Department of Cell Physiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497701              
3Rolf Sprengel Group, Max Planck Institute for Medical Research, Max Planck Society, ou_1497741              
4Olfaction Web, Max Planck Institute for Medical Research, Max Planck Society, ou_1497733              
5External Organizations, ou_persistent22              

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Free keywords: Brain; chemical information transmission; Ion channels in the brain
 Abstract: L-glutamate is the major excitatory neurotransmitter in the vertebrate central nervous system. Most cells are responsive to glutamate which activates cation channels with different pharmacological, kinetic, and ion permeability properties. These channels play important roles in neurotransmission, memory acquisition as well as acute and chronic disorders of the brain. The present report summarizes recent knowledge on AMPA (a-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid) receptors which mediate fast synaptic neurotransmission.

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Language(s): eng - English
 Dates: 1992-02
 Publication Status: Published in print
 Pages: 2
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Degree: -

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Title: Arzneimittel−Forschung
  Alternative Title : Arzneimittel−Forschung
Source Genre: Journal
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Publ. Info: Stuttgart ; New York, NY : Thieme
Pages: - Volume / Issue: 42 (2A) Sequence Number: - Start / End Page: 209 - 210 Identifier: ISSN: 0004-4172