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  Crystallization and preliminary X-ray analysis of the human c-H-ras-oncogene product p21 complexed with GTP analogues

Scherer, A., John, J., Linke, R., Goody, R. S., Wittinghofer, A., Pai, E. F., et al. (1989). Crystallization and preliminary X-ray analysis of the human c-H-ras-oncogene product p21 complexed with GTP analogues. Journal of Molecular Biology (London), 206(1), 257-259. doi:10.1016/0022-2836(89)90540-8.

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JMolBiol_206_1989_257.pdf (Any fulltext), 286KB
 
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 Creators:
Scherer, Anna1, Author              
John, Jacob, Author
Linke, R., Author
Goody, Roger S.2, Author              
Wittinghofer, Alfred2, Author              
Pai, Emil F., Author
Holmes, Kenneth C.2, 3, 4, Author              
Affiliations:
1Department of Biomolecular Mechanisms, Max Planck Institute for Medical Research, Max Planck Society, ou_1497700              
2Emeritus Group Biophysics, Max Planck Institute for Medical Research, Max Planck Society, ou_1497712              
3Protein Cristallography XDS, Max Planck Institute for Medical Research, Max Planck Society, ou_1497735              
4Muscle Research, Max Planck Institute for Medical Research, Max Planck Society, ou_1497731              

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 Abstract: The catalytic domain (amino acid residues 1 to 166) of the human ras-oncogene product p21 complexed with the GTP analogues beta,gamma-imido-GTP (GMPPNP), beta,gamma-methylene-GTP (GMPPCP), and guanosine-5'-(gamma-thiotriphosphate) (GTP gamma S) have been been crystallized. Crystals of the GMPPNP and GMPPCP complexes are well suited for high resolution X-ray crystallography. They belong to space group P3(1)21 (or its enantiomorph P3(2)21) with unit cell axes a=b=40.3 A and c = 162.2 A.

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Language(s): eng - English
 Dates: 1988-08-251988-10-312004-10-281989-03-05
 Publication Status: Published in print
 Pages: 3
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 Table of Contents: -
 Rev. Type: Peer
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Title: Journal of Molecular Biology (London)
  Other : J Mol Biol
Source Genre: Journal
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Publ. Info: London : Academic Press
Pages: - Volume / Issue: 206 (1) Sequence Number: - Start / End Page: 257 - 259 Identifier: ISSN: 0022-2836
CoNE: https://pure.mpg.de/cone/journals/resource/954922646042