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  Long noncoding RNAs usher in a new era in the biology of enhancers

Ørom, U. A., & Shiekhattar, R. (2013). Long noncoding RNAs usher in a new era in the biology of enhancers. Cell, 154(6), 1190-1193. doi:10.1016/j.cell.2013.08.028.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0019-10CF-8 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0019-10D1-F
Genre: Journal Article

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Ørom.pdf (Publisher version), 284KB
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© 2014 Elsevier B.V.
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 Creators:
Ørom, Ulf Andersson1, Author              
Shiekhattar, Ramin2, Author
Affiliations:
1Long non-coding RNA (Ulf Andersson Ørom), Independent Junior Research Groups (OWL), Max Planck Institute for Molecular Genetics, Max Planck Society, Ihnestr. 73, 14195 Berlin, Germany, ou_1479659              
2 The Wistar Institute , Philadelphia, PA 19104, USA, ou_persistent22              

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Free keywords: Animals Chromatin/metabolism *Enhancer Elements, Genetic Humans Promoter Regions, Genetic RNA, Long Noncoding/*metabolism Transcription, Genetic *Transcriptional Activation
 Abstract: Enhancer-associated long noncoding RNAs act over long distances and across chromosomes to activate transcription at distal promoters. Here, we address the latest advances made toward understanding the role of long noncoding RNA expression and the involvement of these RNAs in enhancer function through association with protein factors and modulation of chromatin structure.

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Language(s): eng - English
 Dates: 2013-09-12
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1016/j.cell.2013.08.028
ISSN: 1097-4172 (Electronic)0092-8674 (Print)
URI: http://www.ncbi.nlm.nih.gov/pubmed/24034243
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Title: Cell
Source Genre: Journal
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Publ. Info: Cambridge, Mass. : Cell Press
Pages: - Volume / Issue: 154 (6) Sequence Number: - Start / End Page: 1190 - 1193 Identifier: ISSN: 0092-8674
CoNE: https://pure.mpg.de/cone/journals/resource/954925463183